International Journal of Current Research in Physiology and Pharmacology

Emerging Frontiers and Future Directions in Nanomedicine: A Comprehensive Review

2023-12-10T06:56:42+00:00

Nanomedicine stands at the forefront of healthcare advancements, leveraging nanotechnology to enhance diagnosis, treatment, and disease prevention. Within this rapidly growing field, nanoparticles exhibit unique traits, such as a notable surface area-to-volume ratio and precise targeting abilities, making them valuable in medical applications. The article delves into diverse types of nanomedicines utilized in the pharmaceutical sector, exploring their potential advantages and examining targeted drug delivery mechanisms. Key breakthroughs, like globally recognized therapies such as Doxil and Abraxane, have emerged from nanomedicine. However, it emphasizes the necessity to address regulatory and ethical considerations to ensure both safety and efficacy. The article sheds light on limitations in targeted drug delivery, including issues like limited drug payload capacity and a lack of specificity, emphasizing the importance of addressing these challenges. Despite hurdles, the future of nanomedicine appears promising, poised to revolutionize personalized medicine, elevate disease detection and treatment, and support tissue regeneration and repair. Integration with artificial intelligence is highlighted as a potential avenue for achieving more precise and efficient drug delivery and disease diagnosis. The article underscores the significance of ongoing investments and collaborations among researchers, healthcare providers, and industry partners to surmount obstacles and unlock the full potential of nanomedicine. In conclusion, nanomedicine stands as a dynamic and promising field with the potential to bring about significant improvements in healthcare outcomes.

Keywords: Nanomedicine, Targeted drug delivery system, Treatment, Healthcare, FDA (food and drug administration).

Formulation and evaluation of herbal paediatric edible jelly of Breynia vitis-idea for helminthic infections

2023-12-13T03:32:02+00:00

Aim and Background: This study delves into the exploration of natural anthelmintics to address helminthiasis, a widespread infectious disease caused by parasitic worms. Leveraging the historical use of plants in phytotherapy, the research focuses on the ethanolic extract of leaves of Breynia vitis-idaea for its potential anthelmintic properties. Methodology: The investigation involves phytochemical screening, earthworm bioassays, and the formulation of a child-friendly herbal jelly. Result: The study reveals promising anthelmintic efficacy in ethanolic extract of leaves of Breynia vitis-idaea, particularly at concentrations exceeding 40 mg/mL. The formulated herbal jelly, with Batch F3 exhibiting the desired attributes, offers an appealing solution for parasitic infections in children. The dark green jelly, with a pleasant odor and thick consistency, proves to be a viable alternative to traditional anthelmintic drugs. Conclusion: The study underscores the global shift towards herbal remedies, driven by their natural origin and minimal side effects. In regions with limited access to modern healthcare, the reliance on traditional practitioners and medicinal plants becomes crucial, emphasizing the need to integrate traditional wisdom with scientific validation. As the world faces evolving health challenges, embracing and further exploring the potential of herbal interventions is imperative for resilient and sustainable healthcare systems. The results of this study add to the growing body of evidence that herbal alternatives to conventional anthelmintic drugs are better, especially when it comes to genetic resistance. The study also supports using herbal remedies in healthcare.

Keywords: Breynia vitis-idaea, Anthelmintic activity, Helminthiasis, Jelly.

Formulation and evaluation of herbal face pack for healthy skincare

2023-12-22T08:21:42+00:00

Aim and Background: This research investigates the formulation and assessment of a herbal face pack, integrating historical insights into plant-based skincare remedies. Methodology: Comprising ingredients like neem, multani mitti, turmeric, aloe vera, papaya, liquorice, and rose water, the face pack is designed to enhance skin health and radiance. The study meticulously details the preparation process, emphasizing the incorporation of traditional practices within modern skincare approaches. Comprehensive evaluation encompasses organoleptic, physicochemical, rheological, irritancy, and stability analyses. Result: The outcomes affirm that the face pack has commendable attributes, including a pleasing fragrance, refined texture, and non-irritating properties. Demonstrating sustained stability, the formulation underscores its potential as a natural and efficacious cosmetic product. This research adeptly integrates age-old wisdom with contemporary scientific scrutiny, underscoring the relevance of exploring traditional skincare practices in a contemporary context. Conclusion: The herbal face pack emerges as a promising solution for fostering luminous and resilient skin through the judicious use of natural constituents.

Keywords: herbal skincare, face pack formulation, natural ingredients, skincare research, traditional practices.