International Journal of Current Research in Physiology and Pharmacology (IJCRPP) 2020-05-28T17:14:57-04:00 IJCRPP, Sumathi Publications Open Journal Systems <p><strong>eISSN: 2523-6709,&nbsp;</strong><strong>pISSN: 2523-6695.</strong></p> <p style="text-align: left;">(Logos are embedded with links)</p> <hr> <p style="text-align: left;"><a href=";refid=dcrecen" target="_blank" rel="noopener"><img src="/public/site/images/admin/base.png" alt=""></a> <a href=";publication=International+Journal+of+Clinical+and+Biomedical+Research&amp;publisher_str=Sumathi+Publications&amp;type=Journal+Article" target="_blank" rel="noopener"><img src="/public/site/images/admin/crossref1.png" alt=""></a> <a title="IJCRPP" href=";as_sdt=0%2C5&amp;;oq=site" target="_blank" rel="noopener"><img src="/public/site/images/admin/GoogleScholar1.png" alt=""></a> <a href=";qt=results_page" target="_blank" rel="noopener"><img src="/public/site/images/admin/logo_wcmasthead_en1.png" alt=""></a> <a href="" target="_blank" rel="noopener"><img src="/public/site/images/admin/pkp-index-301.png" alt=""></a> <a href=";la=en" target="_blank" rel="noopener"><img src="/public/site/images/admin/sherparomeo-home.jpg" alt=""></a></p> <hr> <p>International Journal of Current Research in Physiology and Pharmacology (IJCRPP) provides an outlet for research scientists in areas of Health Sciences. IJCRPP is open access, online &amp; Print, peer-reviewed international journal with a primary objective to provide research and applications related to Physiology, Pharmacology and Clinical Medicine.</p> <p>Submitted papers must be in technical English, suitable for scientific publication. All articles have to be original articles that have not been published elsewhere or are being considered for publication in other journals. All articles submitted will be peer-reviewed by experts. Receipt of the manuscript will be acknowledged by email. Every effort will be made to complete the review process within 3 weeks and communicated to the corresponding author. Papers should be submitted electronically on the journal's website. The Editorial Board will strive for the quality of the journal and will also index the journal in various indexing bodies and the information will be updated on the journal website from time to time.</p> <p>We welcome all your submissions.</p> <p>I hope you will consider IJCRPP for your next submission.</p> <p>If any further information is required please mail to:</p> <p><a href="" target="_blank" rel="noopener"></a> or</p> <p><a href="" target="_blank" rel="noopener"></a>.</p> <p>The journal accepts manuscripts in the following forms:</p> <ul> <li class="show">Original research articles</li> <li class="show">Reviews</li> <li class="show">Case reports</li> <li class="show">Short communications</li> <li class="show">Letters to editor</li> <li class="show">Discussion papers</li> <li class="show">Clinical Experience</li> <li class="show">Clinicopathological correlation</li> <li class="show">Book reviews</li> <li class="show">"How to do it" type articles describing new methods or procedures.</li> </ul> <p>Aim :</p> <ul> <li class="show">Our goal is to stimulate new research ideas and foster practical application from the research findings. The journal publishes original research, review articles, case reports of such high quality as to attract contributions from the relevant international communities.</li> </ul> <p>Critical Objective:</p> <ol> <li class="show">To maintain the highest standards of editorial integrity</li> <li class="show">To improve health, health care, and health education, internationally by elevating the quality of medical care, disease prevention, and research</li> <li class="show">To publish original, important, well-documented, peer-reviewed articles on basic medical sciences subject topics</li> <li class="show">To provide doctors with continuing education in basic&nbsp; science to support clinical decisions</li> <li class="show">To enable physicians to remain informed in multiple areas of basic medical science, including developments In the field of health education.</li> <li class="show">To achieve the highest level of ethical medical journalism and to produce a publication that is timely, credible, and enjoyable to read.</li> </ol> <p>Kind Regards,</p> <p>IJCRPP Editorial Team.</p> Comparison of Blood Pressure in Beta Thalassemia Major Patients with that of Control 2020-05-28T17:14:56-04:00 Sneha Mahadev Bhatkar Surendra S Shivalkar Sachin H Mulkutkar <p><strong>Introduction and Objectives : </strong>β-thalassemia major patients need to have repeated blood transfusions throughout their life for survival, which leads to so many complications. Heart disease is the most important complication and the main determinant of survival in these patients. Our study shows comparison of blood pressure between these patients and that of normal subjects.</p> <p><strong>Material and Methods : </strong>Present study was a cross sectional type of study and consisted of 100 normal subjects (control group) and 100 patients of beta thalassemia major (study group). Blood pressure was recorded in both the groups using mercury sphygmomanometer and statistical analysis of the observations was done using Z test.</p> <p><strong>Results : </strong>There was no statistically significant difference in the Systolic blood pressure (SBP) of study group as compared to control group whereas there was a difference in the Diastolic blood pressure (DBP) of study group and control group which was statistically significant (p value &lt;0.0001).</p> <p><strong>Conclusion : </strong>There was an overall reduction in the blood pressure of study group as compared to control group but the difference in SBP was statistically not significant whereas that of DBP was statistically significant.</p> <p><strong>Key Words: </strong>Beta thalassemia major, Diastolic blood pressure, Systolic blood pressure</p> 2020-05-24T21:44:10-04:00 ##submission.copyrightStatement## Physical and Mathematical Model of Heart and Cardiovascular System 2020-05-28T17:14:55-04:00 Aditya Kundu Ananya Kundu Goutam Kumar Kundu <p>The cardiovascular system is modelled as a fluid flow system consisting of networks of pumps and piping systems. A mathematical model relating different cardiovascular parameters was developed. The change in cardiovascular parameters with individuals’ physical activity level, habits and environmental factors was established. The models used to predict how an individual can control the cardiovascular parameters to be healthy and diagnosing problems in the system.<br>Keywords: Blood Pressure; Circulatory system modelling; Heart Rate.</p> 2020-05-24T21:45:25-04:00 ##submission.copyrightStatement## Evaluation of Pulsed Electromagnetic Field in the management of osteoarthritis using Electromyography – An Interventional study 2020-05-28T17:14:57-04:00 Sajuni I karthika M S Ezhilnila Lalitha M. R. Vishnuprasaath S. <p>Knee pain is one of the most frequent musculoskeletal problems among the middle-aged and elderly people and ‘Osteoarthritis’ is the widespread clinical pathology of the knee. <strong>Objective:</strong> The present study was conducted to evaluate whether low frequency Pulsed Electro Magnetic Field (PEMF) therapy is effective in patients with osteoarthritis knee using surface Electromyography (sEMG) of vastus medialis. <strong>Methods</strong><strong>:</strong> The participants were subjected to Pulsed Electromagnetic Field Therapy using the PULSATRON&nbsp; instrument designed by Madras Institute of Magnetobiology, Anna nagar. They were given PEMF therapy of 10 Hz for 60 minutes/ day for 21 days with a break after every 6 days. The participants of the study were subjected to Electromyography of vastus medialis using the MEDICAID PHYSIOPAC machine. The findings are compared before and after the duration of PEMF therapy. <strong>Results</strong><strong>:</strong> The study shows that Low frequency PEMF (10 Hz) can be used as a treatment modality for Osteoarthritis. PEMF therapy, when given for a sufficient time (21 days) can improve the stiffness and the power of muscles as seen by the increase in amplitude of electromyography. The mean amplitude of sEMG in vastus medialis was found to be significantly increased (p &lt;0.001) in the study group following the Pulsed Electro Magnetic Field (PEMF) therapy.</p> 2020-05-24T21:43:58-04:00 ##submission.copyrightStatement## The study of the effects of 12 weeks of yoga training on respiratory pressures and 40 mm Hg test in healthy individuals 2020-05-28T17:14:57-04:00 Deepa HS <p><strong>Background: </strong></p> <p>Yogic exercises have been found to be beneficial for better maintenance of bodily functions even in normal healthy subjects. In view of this, present study was planned to evaluate the effect of Yoga on respiratory pressures and 40 mm Hg test in healthy individuals.</p> <p><strong>Method:</strong></p> <p>The present study included 80 healthy subjects (40 males, 40 females) of 30-40 years age group. Subjects fulfilling the inclusion and exclusion criteria attended a minimum of five Yoga classes per week for a period of twelve weeks. Age, height, weight &amp; BMI of the subjects were recorded. The maximum expiratory pressure, maximum inspiratory pressure and 40 mm Hg test were analysed before &amp; after twelve weeks of Yoga practice. The same subjects were chosen as both study as well as control group in order to minimize the confounding factors and make the study more reproducible. Student’s paired‘t’ test was used to compare the changes in parameters before and after Yoga training.</p> <p><strong>Results:</strong></p> <p>On analysis of results, there was highly significant (p&lt;0.001) increase in maximum expiratory pressure, maximum inspiratory pressure and 40 mm Hg test after twelve weeks of Yoga practise. The response was similar in both the genders.</p> <p><strong>Conclusion:</strong></p> <p>Present study proved that regular practice of Yoga for minimum of 12 weeks is beneficial in improving respiratory pressures and 40 mm Hg test in normal healthy individuals and this improvement is appreciable in both genders. Results of the study would justify the incorporation of Yoga as part of our lifestyle in promoting health. Also Yoga can make an appreciable contribution to primary prevention and management of lifestyle diseases.</p> 2020-05-24T00:00:00-04:00 ##submission.copyrightStatement##