Magnesium Status in Hospitalized ICCU and non ICCU Patients With Special Reference to Waterborne Magnesium

Authors

  • Kirti R Surati Surat Municipal Institute of Medical Education and Research
  • Ramavataram VSS Divvi SBKS Medical Institute and Research Centre Pipariya, Waghodiya, Vadodara
  • ShreeyasPrasad D Nilakhe Surat Municipal Institute of Medical Education and Research
  • Drishty R Surati
  • Vipul Srivastav

DOI:

https://doi.org/10.31878/ijcbr.2019.53.1

Abstract

Introduction:

Low serum magnesium levels in hospitalized patients including those with cardiovascular ailments have been reported by many studies. On the other hand, magnesium therapy is advocated but has not yet been conclusively proved. In our earlier study, an association between waterborne magnesium and hypomagnesaemia in healthy subjects was reported. The present study was aimed at the contribution of waterborne magnesium among filtered and non-filtered water users in hospitalized patients.

Material and methods:

The present study was carried out at SMIMER, Surat. Ethical committee approval was taken. On informed consent, subjects from ICCU and general ward of Medicine unit were selected. Demographic and clinical information was collected. Serum magnesium, cardiac profile and renal profile were analyzed. Patients with conditions such as kidney, liver, brain and other critical illness were excluded. The results were expressed as Mean and SD and appropriate statistical tools were applied to arrive at conclusions. 

Results:

Among total 557 subjects including 185 healthy subjects, 93 ICCU and 279 non-ICCU patients, the incidence of hypomagnesaemia (serum Mg < 1.7 mg/dl) was 18%, 36% and 42% was observed respectively. A significant difference (p < 0.01) in serum magnesium between filtered and non-filtered water users in healthy (1.77 ±0.36 vs 2.01 ±0.48), ICCU  (1.35 ±0.44 vs 1.72±0.55), and in non-ICCU patients (1.51 ±0.59 vs 1.77±0.51) was found. No significant difference was observed in other parameters.

Conclusion:

Significant hypomagnesaemia was observed among users of filtered water as compared to nonfiltered water users in all groups (ICCU, non-ICCU and healthy), strongly suggestive of contribution of waterborne magnesium in maintaining normal status in the population and inadequate levels may be correlated to a higher incidence of myocardial infarction as evident from the present study wherein a 42% prevalence of hypomagnesaemia in ICCU patients was found. 

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Author Biographies

Kirti R Surati, Surat Municipal Institute of Medical Education and Research

Tutor,

Biochemistry Department

Surat Municipal Institute of Medical Education and Research

Near Bombay Market, Umarwada, Surat. 395010

 

Ramavataram VSS Divvi, SBKS Medical Institute and Research Centre Pipariya, Waghodiya, Vadodara

Dr. D. V. S. S. Ramavataram

Professor and Head

Biochemistry Department

Smt. B K Shah Medical Institute & Research Centre & Dhiraj Hospital

At Post Piparia, Waghodia Road,

Taluka: Waghodia, Vadodara 391760.

 Ph.-02668-245264, 245266, 245126

M: 9426566393

ShreeyasPrasad D Nilakhe, Surat Municipal Institute of Medical Education and Research

Assistant Professor

Biochemistry Department

Surat Municipal Institute of Medical Education and Research

Near Bombay Market, Surat. 395010.

Drishty R Surati

Senior Resident

Medicine Department

Government Medical College

Surat. 

Vipul Srivastav

Professor and Head

Medicine Department

Surat Municipl Institute of Medical Education and Research

Near Bombay Market

Surat.

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Published

2019-08-05

Issue

Section

Original Research Articles