Main Article Content
Background: Surgical site infections (SSI) are frequently occurring in postoperative complications. The present study is undertaken to isolate and determine the frequency of distribution of pathogens in post-operative wound infections and the antimicrobial susceptibility pattern of the causative organisms. Methods: This cross-sectional, prospective study was carried out over a period of one year. 250 pus samples from cases of surgical site infections were processed for gram staining, culture, biochemical identification tests, and antimicrobial susceptibility testing. Results: Out of 250 patients of post-operative wound infections, 48 are cultured positive, among which 21 were gram-positive, and 27 were gram-negative. Staphylococcus aureus emerged as the commonest etiological agent 17 (35.42%) followed by Pseudomonas aeruginosa 14 (29.17%), E.coli 6 (12.5%). Amikacin (72.9%) was found to be the most effective antibiotic, and Multidrug resistance was observed with staphylococcus aureus (79.16%) and pseudomonas aeruginosa (83.3%). Conclusions: Staphylococcus aureus is the commonest etiological agent for Postoperative wound infections. Antibiotic susceptibility pattern of various isolates helps in proper selection of antibiotics and in this study, it was found that Amikacin was the most effective antibiotic against postoperative wound infections.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
The submitted papers are assumed to contain no proprietary material unprotected by patent or patent application; responsibility for technical content and for protection of proprietary material rests solely with the author(s) and their organizations and is not the responsibility of the journal. The main (first/corresponding) author is responsible for ensuring that the article has been seen and approved by all the other authors. It is the responsibility of the author to obtain all necessary copyright release permissions for the use of any copyrighted materials in the manuscript prior to the submission.
What are my rights as an author?
It is important to check the policy for the journal to which you are submitting or publishing to establish your rights as
Author. Journal's standard policies allow the following re-use rights:
- The journal allows the author(s) to hold the copyright without restrictions.
- The journal allows the author(s) to obtain publishing rights without restrictions.
- You may do whatever you wish with the version of the article you submitted to the journal.
- Once the article has been accepted for publication, you may post the accepted version of the article on your own personal website, your department's website or the repository of your institution without any restrictions.
- You may not post the accepted version of the article in any repository other than those listed above (i.e. you may not deposit in the repository of another institution or a subject-matter repository) until 12 months after publication of the article in the journal.
- You may use the published article for your own teaching needs or to supply on an individual basis to research colleagues, provided that such supply is not for commercial purposes.
Raza MS, Chander A, Ranabhat A. Antimicrobial susceptibility patterns of the bacterial isolates in post- operative wound infections in a tertiary care hospital, Kathmandu, Nepal. Open Journal of Medical Microbiology. 2013; 3:159-63
Mengesha RE, Kasa BG, Saravanan M, Berhe DF, Wasihun AG. Aerobic bacteria in post surgical wound infections and pattern of their antimicrobial susceptibility in adyer Teaching and Referral hospital, Mekelle, Ethiopia. BMC Research Notes. 2014;7:575-80
Dessalegn L, Shimells T, Tadesse E, Selassie SG. Aerobic bacterial isolates from post- surgical wound and their antimicrobial susceptibility pattern: a hospital based cross-sectional study. Journal of Medical Research. 2014; 3:18-23
Amrita S, Sheetal R, Narendra N. Aerobic Microorganisms in post operative wound infections and their antimicrobial susceptibility pattern. Journal of Clinical and Diagnostic Research. 2010; 4:3392-6
Edmiston CE, Seabrook GR, Johnson CP, Paulson DS, Beausoleil CM. Comparative of a new and innovative 2 percent chlorhexidine gluconate-impregnated cloth with 4 percent Chlorhexidine gluconate as topical antiseptic for preparation of skin prior to surgery. Am J Infect Control. 2006; 35(2): 89-96
Haley RW, Culver DH, Morgan WM, Emori TG, Munn VP, Hooten TM. Identifying patients at high risk of surgical wound infection: a simple multivariate index of patient’s susceptibility and wound contamination. Am J Epidemiol. 1985;121:206-15
Forbes BA, Sahm DF, Weissfeld AS. Bailey and Scott’s Diagnostic Microbiology. 10th ed. St. Louis, Misssouri, USA: Mosby Inc; 1998
CLSI: Performance Standards for Antimicrobial Susceptibility Testing; Twentieth Informational Supplement CLSI Document M100–S20. Wayne, PA: Clinical and Laboratory Standards Institute; 2010
Suljagić V, Jevtic M, Djordjevic B, Jovelic A. Surgical site infections in a tertiary health care center: Prospective cohort study. Surg Today 2010;40:763-71
Desa LA, Sathe MJ. Factors inﬂuencing wound infection (a prospective study of 280 cases). J Postgrad Med. 1984;30:231-6
Chakarborty SP, Mahapatra SK, Bal M, Roy S. Isolation and identification of vancomycin resistant Staphylococcus aureus from postoperative pus sample. Al Ameen J Med Sci. 2011;4(2):152-68
Ananthi B, Ramakumar M, Kalpanadevi V, Abigail RS, Karthiga L, Victor HK, et al. Aerobic bacteriological profile and antimicrobial susceptibility pattern in post-operative wound infections. Int J Medi Sci Clin Inven. 2017;4(2):2702-6
Isibor OJ, Oseni A, Eyaufe A. Incidence of aerobic bacteria and Candida albicans in postoperative wound infections. Afr J microbial Res. 2008;2:28891
Lilani SP, Jangale N, Chowdhary A, Daver GB. Surgical site infection in clean and cleancontaminated cases. Indian J Med Microbiol. 2005;23:249-52
Onche, O. Adedeji, Microbiology of post operative surgery wound infection in implant surgery. Nigerian journal of Surgical research, 2004;6(1-2): 37-40.
Jamali AR. post operative wound infections in orthopedic surgery, J. Coll Physicians Surg pak 2001;11(12):747-9