EVALUATION OF GLYCOSYLATED HEMOGLOBIN AND ELECTROLYTE STATUS IN DIABETIC KETOACIDOSIS
Abstract
Background: The present study was conducted to evaluate glycosylated hemoglobin and electrolyte status in Diabetic ketoacidosis subjects compared with controlled type II diabetes mellitus. Methods: Totally 100 subjects were included in this study (75 known DKA subjects and 25 controlled type II Diabetes Mellitus subjects). 5ml of venous blood samples are collected from subjects, Biochemical parameters performed Fasting blood sugar, Post prandial blood sugar by Glucose oxidase and peroxidase method, Glycosylated hemoglobin by Ion exchange High performance liquid chromatography, serum electrolytes levels are estimated by Ion selective electrode method. Results: The serum levels of FBS, PPBS, HbA1c levels are high in DKA compared with controlled Type II DM. the serum levels of sodium are significantly decreased in DKA compared with controlled Type II DM. The serum levels of potassium and chloride are high in DKA compared with controlled Type II DM. Conclusion: We concluded that electrolyte imbalance is high in DKA due to hyperglycemic hyper-osmolality and insulin deficiency frequently leads to electrolyte imbalance. HbA1c, FBS, PPBS levels are elevated in DKA due to uncontrolled hyperglycemia.
KEYWORDS: Peroxidase method; Fasting blood sugar; HbA1c; Glycosylated hemoglobin.
Downloads
Downloads
Published
Issue
Section
License
The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
The submitted papers are assumed to contain no proprietary material unprotected by patent or patent application; responsibility for technical content and for protection of proprietary material rests solely with the author(s) and their organizations and is not the responsibility of the journal. The main (first/corresponding) author is responsible for ensuring that the article has been seen and approved by all the other authors. It is the responsibility of the author to obtain all necessary copyright release permissions for the use of any copyrighted materials in the manuscript prior to the submission.
What are my rights as an author?
It is important to check the policy for the journal to which you are submitting or publishing to establish your rights as
Author. Journal's standard policies allow the following re-use rights:
- The journal allows the author(s) to hold the copyright without restrictions.
- The journal allows the author(s) to obtain publishing rights without restrictions.
- You may do whatever you wish with the version of the article you submitted to the journal.
- Once the article has been accepted for publication, you may post the accepted version of the article on your own personal website, your department's website or the repository of your institution without any restrictions.
- You may not post the accepted version of the article in any repository other than those listed above (i.e. you may not deposit in the repository of another institution or a subject-matter repository) until 12 months after publication of the article in the journal.
- You may use the published article for your own teaching needs or to supply on an individual basis to research colleagues, provided that such supply is not for commercial purposes.