Review Articles

RECURRENT PREGNANCY LOSS AND ASSOCIATION OF MTHFR, PAI-1 AND ACE GENE POLYMORPHISMS IN WOMEN

Authors

  • Snehlata Pandey
  • Archana Pandey
  • U.K. Chauhan
  • Arvind Tripathi
  • Jitendra Tripathi
  • Sanjeev Dubey
  • Rishabh Deo Saket
Author affiliations
  • Snehlata Pandey
  • Archana Pandey
  • U.K. Chauhan
  • Arvind Tripathi
  • Jitendra Tripathi
  • Sanjeev Dubey
  • Rishabh Deo Saket
Published: 2015-10-28 Volume 1, Issue 4; October 2015

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Abstract

Recurrent pregnancy loss (RPL) is a significant clinical problem that may occur before the 20th week of gestation. There is no general consensus on how many consecutive abortions are considered as RPL. The goal of this study is to investigate the correlation between recurrent miscarriage (RM) and common polymorphisms in angiotensin-converting enzyme (ACE), plasminogen activator inhibitor 1 (PAI-1) and Methylenetetrahydrofolate Reductase (MTHFR) genes among women experiencing RM. The literature existing in different population was searched and based on these finding we conclude that polymorphism in either one of these genes may increase chances of miscarriage.

KEYWORDS: Polymorphism; Recurrent pregnancy; Plasminogen activator inhibitor 1.

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Published

2015-10-28

Issue

Volume 1, Issue 4; October 2015

Section

Review Articles

License

The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.

How to Cite

RECURRENT PREGNANCY LOSS AND ASSOCIATION OF MTHFR, PAI-1 AND ACE GENE POLYMORPHISMS IN WOMEN. (2015). International Journal of Clinical and Biomedical Research, 1(4), 50-55. https://sumathipublications.com/index.php/ijcbr/article/view/93