EFFECT OF THREE MONTHS COURSE OF DAILY TERIPARATIDE INJECTION ON OSTEOPOROSIS IN A RURAL POPULATION: A ONE YEAR FOLLOW UP STUDY USING pDEXA

Abstract

Osteoporosis continues to represent a significant public-health problem, especially in the rural setting, where access to the availability of sophisticated diagnosis and treatment options limited. Awareness, knowledge and long term consequences, and the importance of calcium supplementation are often inadequate among rural population. Additionally, inadequate finances are also a significant barrier towards patient compliance, which increases disease burden and the risk of fractures. The present study aim is to test the intervention on the effects of a three-month trial of daily intramuscular teriparatide (20µg) administered subcutaneously on the patients with osteoporosis in a rural community. Then treatment outcomes assessed using peripheral dual-energy X-ray absorptiometry (pDEXA; EXA 3000). The study patients with osteoporotic cracks in the spine were included people who experienced spinal fractures. Inj teriparatide intervention was administered three months daily as SC injections. Patients were followed by regular follow-up up to 3 months and pDEXA measurements at a year time. The findings of the study helped to improve the knowledge of teriparatide effectiveness for the treatment of osteoporosis in the rural population and provided evidence to support therapeutic interventions to develop feasible and effective osteoporosis management strategies.